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The Ethics of Personalised Medicine: Critical Perspectives

The Ethics of Personalised Medicine: Critical Perspectives

  • 作者:
  • 出版商: Routledge
  • ISBN: 9781472447968
  • 出版时间 May 2015
  • 规格: Hardback
  • 适应领域: U.K. ? 免责申明:
    Countri(es) stated herein are used as reference only
¥1,586.25
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  • 描述 
  • 大纲 
  • 详细

    In recent times, the phrase a "personalised medicine has become the symbol of medical progress and a label for better health care in the future. However, a controversial debate has developed around whether these promises of better, more personal and more cost-efficient medicine are realistic. This book brings together leading researchers from across Europe and North America, from both normative and empirical disciplines, who take a more critical view of the often encountered hype associated with personalised medicine.

    Partially drawing on a four year collaborative research project funded by the German Ministry for Education and Research, the book presents a multidisciplinary debate on the current state of research on the ethical, legal and social implications of personalised medicine. At a time when future health care is a topic of much discussion, this book provides valuable policy recommendations for the way forward. This study will be of interest to researchers from various disciplines including philosophy, bioethics, law and social sciences.

  • Introduction, Jochen Vollmann, Verena Sandow, Sebastian Wascher and Jan Schildmann
    Part I: Personalised Medicine
    Medicine for the Person? Concepts and Contextual Aspects: What is personalised medicine? Sharpening a vague term based on a systematic literature review, Sebastian Schleidgen, Corinna Klingler, Teresa Bertram, Wolf H. Rogowski and Georg Marckmann
    Alarming symptoms of a paradigm shift? An approach to bridge the gap between hypothetical ethics and the current status of individualised medicine research, Tobias Fischer, Marcus Dorr, Robin Haring and Martin Langanke
    Personalised medicine: getting past the controversies, George P. Browman
    Patient as person in personalised medicine: autonomy, responsibility and the body, Thomas Wabel
    The authority of corporeality and emotions: the new phenomenology and its relevance to the German debate on personalised medicine, Mathias Wirth
    Towards integration of 'personalised' and 'person-centred' medicine: the concept of 'integrative and personalised health care', Peter Heusser
    Part II: Personalised Medicine in Clinical and Practical Research
    Ethical considerations for developing a best-practice guideline for next generation sequencing in oncology, Eva C. Winkler, Klaus Tanner, Hanno Glimm and Christof von Kalle
    Practice variation across consent templates for biobank research: a survey of German biobanks, Irene Hirschberg, Hannes Kahrass and Daniel Strech
    Individualised medicine in the diagnosis and prognosis of patients younger than 65 years with normal karyotype acute myeloid leukemia: a systematic review and meta-analysis of the impact of Fms-related tyrosine kinase 3 internal tandem duplication (FLT3-ITD), Matthias Port, Miriam Bottcher, Felicitas Thol, Nicole Trachte, Jurgen Wasem, Arnold Ganser, Laura Pouryamout and Anja Neumann
    Taking it personally: patients' perspectives on personalised medicine and its ethical relevance, Sabine Wohlke, Julia Perry and Silke Schicktanz
    'Personalised medicine' in oncology: physicians' perspectives on contributions to and challenges for clinical practice, Sebastian Wascher, Jan Schildmann, Caroline Brall and Jochen Vollmann
    Through thick and big: data-rich medicine in the era of personalisation, Barbara Prainsack
    Part III Personalised Medicine in Health-Care Systems
    Benefit assessment of personalised interventions: methodological challenges and approaches to a solution, Jurgen Windeler and Stefan Lange
    The relevance of the analytic validity of genetic biomarker tests in personalised medicine in oncology, Franz Hessel
    Approval and reimbursement of personalised drugs: interim results of the adjustment process, Michael Noweski, Anke Walendzik, Franz Hessel, Rebecca Jahn and Jurgen Wasem
    Criteria for fairly allocating scarce health-care resources to genetic tests: which matter most?, Wolf H. Rogowski, Scott D. Grosse, Jorg Schmidtke and Georg Marckmann
    Personalised medicine as orphan drugs? Legal and ethical questions, Sina Gottwald and Stefan Huster
    Personalised medicine: priority setting and opportunity costs in European public health-care systems, Jochen Vollmann
    Part IV Personalised Medicine in Oncology
    Recommendations for Future Development: 'Personalised medicine': multidisciplinary perspectives and interdisciplinary recommendations on a framework for future research and practice, Jan Schildmann, Miriam Bottcher, Maria Gabriel, Arnold Ganser, Sina Gottwald, Franz Hessel, Stefan Huster, Rebecca Jahn, Anja Neumann, Michael Noweski, Matthias Port, Laura Pouryamout, Verena Sandow, Felicitas Thol, Sebastian Wascher, Anke Walendzik, Jurgen Wasem and Jochen Vollmann
    Index.

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